About Us

Second Opinion Physician is an online holistic medical service providing one-on-one phone and Skype consultation, lab testing and assessments plus detailed supplements plan.

Our area of focus is functional medicine, epigenetics and orthomolecular psychiatry. Working by phone and skype is a convenience that saves money and time to patient and practitioner.

Mood and behavioral conditions we have expertise in treating include depression, anxiety, ADHD, biopolar disorder, autism, dementia.

Dr David Epstein, D.O. is certified in the administration of the Walsh Protocol which addresses methylation status, pyrrole disorder, copper toxicity, zinc deficiency, homocysteine and Vitamin D status.

He also embraces the Jack Kruse MD approach to Epi-Paleo Rx diet and reversal of inflammation and auto-immunity. These conditions lead to metabolic syndrome and are caused primarily by stress and a grain based diet. We utilize high level testing to identify imbalances in cortisol/adrenal, thyroid, leptin, insulin, sex hormones, digestive health and elevated HS CRP.

Meet Dr. Dave

Dr Dave is a licensed, physician and telemedicine coach focusing on mood and behavioral disorders. Having earned his degree at the Texas College of Osteopathic Medicine, Dr Dave has been practicing of over a span of 30 years with emphasis on holistic, integrative medicine. David Epstein DO has an extensive history in managing general health conditions related to hormone imbalances, digestive disorders, inflammatory conditions, immunity and musculoskeletal conditions. Treatment modalities have included IV chelation therapy, IV Vitamins, homeopathy, herbal medicine, bio-identical hormonal therapy, colon therapy, detoxification strategies and oxidative therapy.

In 2014 Dr Epstein founded Second Opinion Physician, P.C. With Second Opinion Physician, our focus is on addressing imbalances in brain chemistry and applying the Walsh Protocol to improve nutrient status. Conditions that are particularly responsive to this approach include the 5 biotypes of depression, alcoholism, anxiety, anger, PTSD, schizophrenia, autism, bipolar manic depression, insomnia, dementia, ADHD. Quite often, with mood and behavior disorders there is an often an underlying imbalance related oxidative stress, over or undermethylation (epigenetics), copper elevation, zinc deficiency and pyrroluria.

dr epstein walsh practitioner
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Free Pre-Consultation or General Inquiry

Mood and Behavior Disorders Treated

  • Addiction
    Alcohol Abuse
    Anger Management
    Antisocial Personality
    Asperger’s Syndrome
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  • Bipolar Disorder
    Borderline Personality
    Chronic Relapse
    Developmental Disorders
    Drug Abuse
    Eating Disorders
    Emotional Disturbance
    Learning Disabilities
    Medication Management
    Narcissistic Personality
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  • Obesity
    Obsessive-Compulsive (OCD)
    Oppositional Defiance
    Sleep or Insomnia
    Substance Abuse
    Suicidal Ideation
    Trauma and PTSD
    Weight Loss
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To understand more about the Walsh Protocol for mood and behavioral disorders and learn how it may be of help toyou or a loved one, follow our blog and be sure to get a copy of Dr Walsh’s revolutionary book Nutrient Power; Heal Your Biochemistry and Heal Your Brain.  Through analysis of over 50,000 patient labs profiles, his collective research has established a clear nutritional strategy for correcting improving ones neurotransmitter status through balancing underlying brain chemistry issues.

Learn more about our protocol and fees here.


Gez Agolli NMD, PhD, DrPH

Dr Dave is a talented compassionate integrative physician. He places his patients 1st and utilizes cutting edge therapies that help patients regain optimal health. I enjoyed working along side him and I highly endorse his clinical skills. Not only do I recommend that patients see him but I myself as an integrative physician would consult with him about my own healthcare needs . Dr Dave is definitely practicing tomorrows medicine today.

Gez Agolli NMD, PhD, DrPHManaging Director at Progressive Medical CenterMaxmanc Inc
Anita B.

Dr. Epstein came to our community as a family practice physician in the late 80s. I noticed that he was an osteopath, with a respectful, holistic approach to treating the body. Our community was so grateful that he chose to be our doctor.  It was the birth of my son that made me question the medical model of treating symptoms in the body rather than supporting our bodies so they in turn are able to take care of us. Dr Dave was personable, intelligent and forward thinking.

Flash forward now, 25 years later. My son grew up to struggle with crushing depressions that happened in college which led to a very serious addiction that has been fought like a wild fire for the past 8 years. From the beginning, my son sought help…taking himself to rehabs, supportive living homes, 12 steps, psychiatrists, addiction specialist, nothing seemed to work for very long….Something would come along and snatch him from his periods of recovery, with his addiction taking hold dangerously stronger each time.

I thought to seek the help of Dr. Epstein, after seeing some of the research he was presenting on epigenetics and brain chemistry. My son was very happy to work with Dr. Dave thinking of him as his childhood doctor. He was not doing very well at all, and I did not think he would survive this relapse. If you could have seen him the day; I traveled 9 hours to assist him to get his blood work completed for Dr Dave. He was frail, fragile, frazzled and unable to get thru a day un-medicated, and in a very precarious state. He was unable to arrange to get to the lab for blood work….

It has been 5 months now. The supplement regime is intense and in the past two months, his improvement is astounding.

I wish every person that suffered with depression, anxiety, addiction could have access to such a model of care surrounding addiction. I am surprised that mainstream treatment centers do not include this in their treatment. I regret that we listened to and relied soley upon them and spend thousands of dollars.

I am pleased to share this story and report that today, my son is happy, engaged in life, and for the first time I am seeing him grow in leaps and bounds. I hope that my writing this will help other families who have a loved one who struggles. The brain is a miraculous and mysterious organ.

I’m so thankful there are those out there who are doing this work and am grateful for Dr. Dave who stands up in the face of the tragedy of modern medicine. Dr. Dave still believes in the body’s inherent ability to be well, without dependency on medications. It is a wonderful and heartfelt thing to know he is still our Dr. after all these years.

Anita B.Patient of Dr Dave