Cognoscopy Panel #1 – Primary Markers plus Histamine
When testing the entire set of Cognosocpy Panels, if not doing them all at once, this is the best first place to start. What is not typically ordered with Bredesen’s panel is the histamine. Histamine is tested per the Walsh Approach to assess methylation status. ecause methylation is so relevant to brain function and Alzheimer’s Disease, these two items are added and this panel is referred to as the Cognoscopy Walsh Panel.
- Histamine, Whole Blood – recognized as a most useful indicator of ones methylation status. As opposed to DNA SNP’s which attempt to predict methylation status.
- Copper, Serum – Elevated copper indicates there is an oxidative burden on the body
- Ceruloplasmin – When drawn simultaneously with copper, it is useful in determining one’s level of ‘free copper’.
- Zinc, Plasma – Zinc is involved in over 300 metabolic functions of the body. Not least of which is the production of serotonin and dopamine, the removal of copper and the production of ceruloplasmin.
- Vitamin D – Vitamin D status is positively associated with DNA methylation. DNA methylation is a mechanism used by cells to regulate gene expression. Vitamin D3 supplementation increases DNA methylation in a dose-response manner in persons with vitamin D deficiency.
- Homocysteine– Homocysteine is tested with as part of the Walsh Panel in order that therapy for undermethylation does not result in higher levels of homocysteine. It is a marker of cardiovascular inflammation so treatment with methylation supplementation may increase levels and increase risk of cardiovascular incident.
- CBC – Complete Blood Count – red blood cell with differential
- Metabolic Chemistry Panel – Comprehensive Blood Chemistry including liver, kidney, glucose markers
With your order, you will receive a urine kit for testing kryptopyrroles, which will shipped to you by DHA laboratories. Blood will be drawn at a nearby laboratory for which you will receive a requisition form showing that you’ve paid. Results will be sent to you via a secure HIPAA compliant email.
Video interview – research and protocols of Dr Dale Bredesen.