Understanding Pyrrole Disorder (Pyroluria):

Pyrrole disorder, also known as pyroluria or kryptopyrrole disorder, is a metabolic condition where the body produces excessive kryptopyrrole, a byproduct of hemoglobin breakdown. These kryptopyrroles bind to essential nutrients like zinc and vitamin B6, often leading to a deficiency of these nutrients. Pyrrole disorder can be acquired in utero or early childhood and is often exacerbated by physical or emotional stress, increasing the body’s demand for specific nutrients. If a positive pyroluria test is present along with pyroluria symptoms, testing for low zinc and high copper is advised. A link below is provided to purchase supplements for pyrroluria.

Symptoms of Pyrrole Disorder:

Common pyroluria symptoms include:

Mental health challenges:

Anxiety, depression, agitation, poor stress resilience, and social anxiety

Physical signs:

Poor immune function, slow wound healing, stretch marks, eczema, and nutrient malabsorption, delicate facial features, hypermobile joints

Cognitive and behavioral concerns:

Difficulty focusing, poor academic performance, ADHD-like symptoms, erratic sleep and eating patterns

Vision:

Poor night vision

These symptoms may worsen under stress, as the need for proper nutrient support rises.

About the Pyroluria Test:

This test, conducted by DHA Labs of Chicago, measures urinary kryptopyrroles to assess the likelihood of pyrrole disorder. The kit will be mailed directly to you with complete instructions, a prepaid return envelope, and necessary materials to complete the test from home. Results will indicate whether further testing for copper overload is recommended, as the zinc deficiency commonly seen in pyroluria can lead to an imbalance of copper.