Silvia Menendez Cepero, MD - Cuban Physician
Dr Cepero introduced ozone therapy in Cuba in 1986. She is a consultant the field of ozone medical applications. Her accomplishments include 40 theses of medicine in the areas of biology, pharmacology, medical urgency, traditional and natural medicine, bioenergetic medicine and in dentistry urgency. Cepero is the author of more than 50 articles, published in peered review journal and holds two patents and two medicine registrations for oral and topical OLEOZON® and a new therapeutic indication (topic OLEOZON® for the treatment of impetigo).
This video provides an in-depth explanation of the mechanism of action behind ozone therapy. Ozone, a powerful oxidative agent, reacts selectively by attacking double bonds in molecules, producing unstable compounds that break down into biologically active metabolites such as aldehydes and hydrogen peroxide. These metabolites are responsible for stimulating the body's antioxidant defense systems.
The speaker introduces the concept of oxidative preconditioning, where controlled doses of ozone induce a mild and temporary oxidative stress. This process stimulates the body's natural antioxidant defenses, preparing it to face more severe conditions mediated by reactive oxygen species (ROS), similar to how a vaccine trains the immune system. This oxidative stress, when properly managed, enhances oxygen delivery, immune modulation, and the release of growth factors that promote healing.
In the early phase, ozone interacts with reactive oxygen species, improving oxygen delivery to red blood cells and modulating immune responses via leukocytes. In the late phase, ozone generates lipid oxidation products, which act as redox signaling molecules influencing various biochemical pathways. These molecules support nitric oxide modulation, stem cell activation, and the formation of highly efficient red blood cells.
Ozone therapy plays a key role in maintaining the cellular redox balance, critical for fighting infections and preventing conditions associated with chronic oxidative stress, such as cancer, heart disease, neurodegenerative diseases like Parkinson's and Alzheimer's, and more. The therapy aims to revert excessive oxidative stress and restore balance, reducing the risk of chronic conditions.
The video concludes with insights into animal model studies that validate the therapeutic effects of ozone therapy on diseases involving oxidative stress. These peer-reviewed studies demonstrate ozone's ability to stimulate the body's antioxidant defenses and promote a healthy redox balance without causing further damage.